| Second XI Knock-out Fixtures 2010 | |||
| First Round - 15th June 2010 | |||
| Game Ref. | Home Team | Away Team | |
| 1 | Potten End Res | V | Bye |
| 2 | Waddesdon Res | V | Widmer End SM |
| 3 | Prestwood Res | V | Cadmore End Res |
| 4 | The Lee Res | V | Ballinger Res |
| 5 | Haddenham Res | V | Lacey Green Res |
| 6 | Aylesbury Town Res | V | Holmer Green Res |
| 7 | Bradenham Res | V | Downley Res |
| 8 | Ley Hill Res | V | Bye |
| Quarter Finals - 29th June 2010 | |||
| Game Ref. | Home Team | Away Team | |
| Q1 | Cadmore End Res | V | Downley Res |
| Q2 | Waddesdon Res | V | The Lee Res |
| Q3 | Potten End Res | V | Holmer Green Res |
| Q4 | Ley Hill Res | V | Haddenham Res |
| Semi-Finals - 13th July 2010 | |||
| Game Ref. | Home Team | Away Team | |
| S1 | Cadmore End Res | V | Haddenham Res |
| S2 | Waddesdon Res | V | Holmer Green Res |
| Final - 5th. Sept.2010 11:00 At Aylesbury Town | |||
| Final Reserve Date - 12th. Sept. 2010 11:00 | |||
| Game Ref. | Home Team | Away Team | |
| F | Cadmore End Res | V | Holmer Green Res |